Santa Fe Chicken Skillet is my weeknight secret weapon—bold Tex-Mex flavor, one-pan convenience, and just a handful of ingredients. As a professional chef who built Cookeroni to help busy moms and professionals get nourishing dinners on the table fast, I designed this skillet for chaos-free weeknights. Sear chicken to a golden crust, fold in Ro-Tel, corn, and black beans, then melt cheese for a cozy, satisfying finish. This dish scales up or down, adapts to spice preferences, and makes meal prep feel doable even on the busiest days. Read on to see how this one-pan wonder can transform your weeknights with flavor and ease.
Table of Contents
What makes this Santa Fe Chicken Skillet special
Santa Fe Chicken Skillet is my weeknight ally. It packs bold Tex-Mex flavor into one pan and uses a short ingredient list, which is a blessing on crowded evenings. I love how it turns chaos into dinner in about 30 minutes.
It’s a dish you can rely on when days run late. You’ll taste Santa Fe Chicken Skillet in every bite, and the aroma lifts the mood.
A quick weeknight solution Santa Fe Chicken Skillet
A quick weeknight solution, this skillet shines when time is tight. It cooks fast, feeds a family, and leaves room for your evening plans.
One-pan convenience
One-pan convenience means less cleanup and more table time. I sear the chicken, then simmer Ro-Tel, corn, and beans in the same pan. Flavor builds with every quick flip.
Bold Tex-Mex flavors with accessible ingredients
Bold Tex-Mex flavors come from pantry staples you already have. Ro-Tel, corn, black beans, and cheese create cozy, crowd-pleasing layers.
Why You’ll Love This Santa Fe Chicken Skillet
I reach for this skillet on chaotic evenings because it delivers big flavor in record time. In one pan I get seared chicken, melty cheese, and a cozy Tex-Mex glow.
Easy, family-friendly dinner that keeps weeknights simple (Santa Fe Chicken Skillet)
It’s kid-pleasing and easy for even novices. The pantry comes to your rescue, so cleanup stays light and quick.
Perfect size for busy moms and professionals
Four servings hit the mark for a family without leftovers. It fits a busy schedule.
Flexible leftovers that reheat beautifully
Leftovers reheat beautifully, serving over rice or greens for easy lunches.
Ingredients
Here’s what you’ll need for the Santa Fe Chicken Skillet. I keep the list short to save time.
These ingredients deliver bold Tex-Mex flavor and a cozy melt in one pan.
- 4 boneless, skinless chicken breasts
- 2 tbsp olive oil
- 1 tsp chili powder
- 1 tsp cumin
- ½ tsp paprika
- ½ tsp garlic powder
- Salt and pepper, to taste
- 1 (10 oz) can Ro-Tel diced tomatoes with green chilies
- 1 cup corn kernels (fresh, frozen, or canned)
- 1 cup canned black beans, drained and rinsed
- 1 cup shredded cheddar or Monterey Jack cheese
- 2 tbsp chopped cilantro
- Juice of ½ lime
Exact quantities are listed above and printable at the bottom of the article.
What you’ll need for the skillet
This skillet uses simple stars: chicken, Ro-Tel, corn, black beans, and cheese. Together they become a bold Tex-Mex hug in one pan.
Ingredient notes and substitutions
- Chicken: 4 breasts; boneless, skinless. Use thighs if you prefer, adjusting time.
- Olive oil: 2 tbsp; substitute avocado oil for higher heat.
- Spices: chili powder 1 tsp, cumin 1 tsp, paprika ½ tsp, garlic powder ½ tsp.
- Salt and pepper: to taste; season generously, then taste before serving.
- Ro-Tel: 10 oz can; if unavailable, use diced tomatoes with green chilies and add jalapeño.
- Corn: 1 cup; fresh, frozen, or canned. Drain canned if needed.
- Black beans: 1 cup; drained and rinsed for best texture.
- Cheese: 1 cup; cheddar or Monterey Jack. For dairy-free, use a plant-based cheese.
- Cilantro: 2 tbsp; chopped fresh.
- Lime: juice of ½ lime; add more after tasting.

How to Make Santa Fe Chicken Skillet
Step 1 : Season and sear the chicken
I pat the chicken dry and season it well with chili powder and cumin.
Then I add paprika and garlic powder, plus salt and pepper.
I heat two tablespoons of olive oil in a wide skillet over medium-high.
I add the chicken and sear five to six minutes per side until golden.
We want a crust that stays juicy inside.
Step 2 : Build the Ro-Tel, corn, and black beans
With the chicken set aside, I stir in Ro-Tel, corn, and black beans for a Tex-Mex glow.
I simmer three to four minutes to blend flavors and heat through.
Taste and adjust salt if needed.
Step 3 : Return chicken and melt cheese
I return the chicken to the pan and spoon the sauce over it.
I sprinkle cheese on top and cover the skillet to melt.
If the sauce looks dry, I splash in a splash of water or broth.
Step 4 : Finish with lime and cilantro
A final squeeze of lime brightens the dish, followed by cilantro.
Taste and adjust salt as needed; serve warm with rice, tortillas, or greens.
This is a cheerful finish that invites seconds.
Tips for Success
Quick flavor boosters
- Bloom spices in oil for 30 seconds before searing to wake flavors in your Santa Fe Chicken Skillet.
- Finish with a squeeze of lime and chopped cilantro for brightness.
- Optional: a pinch of cayenne for a subtle kick.
- Taste and adjust salt at the end; flavors sharpen as they rest.
Make-ahead and timing tips
- Premeasure spices the night before for speed.
- Chop cilantro and lime ahead and refrigerate in a small container.
- Cook rice or greens ahead of time for quick serving.
Equipment Needed
- 12-inch skillet (cast iron or nonstick) for searing.
- Spatula and tongs for turning.
- Measuring spoons and cups; knife and cutting board for prep.
- Optional lid or foil to melt cheese.
Essential gear
- 12-inch skillet (cast iron or nonstick) for searing and finishing.
- Spatula and tongs for turning and serving.
- Measuring spoons and cups; knife and cutting board for prep.
- Optional lid or foil to help melt cheese.
Smart substitutions
- If you don’t own a skillet, use a larger pan.
- Avocado oil works well; avoid overpowering EVOO.
- Frozen corn or canned beans keep prep quick.

Variations
These variations let me tailor the Santa Fe Chicken Skillet to spice levels, dietary needs, and what I have on hand. I reach for them when I want a new twist without derailing the weeknight clock.
Spice level and heat variations
- For milder heat, reduce chili powder to ½ teaspoon and use mild Ro-Tel.
- Lean into a medium kick by adding a few jalapeño slices or a pinch of cayenne.
- Go bold with 2 teaspoons chili powder or a touch of chipotle powder.
- Finish with a quick squeeze of lime and a sprinkle of cilantro to balance the heat.
Dairy-free or lighter options
- Skip the cheese and top with avocado slices for creaminess and richness.
- Use dairy-free cheese or a plant-based crema to keep it dairy-free.
- Reduce cheese by half if you want a lighter, less indulgent dish.
- Serve over greens or cauliflower rice to cut extra calories without losing flavor.
Protein substitutions
- Chicken thighs: keep the same pan method, but sear longer (about 6–8 minutes per side) for juicier results.
- Ground turkey: crumble and brown, then mix with Ro-Tel and beans before topping with cheese.
- Shrimp: add in the final 2–3 minutes, just until pink and opaque.
- Other proteins: small dice of pork or beef work if you season with similar Tex-Mex spices.
- Vegetarian option: crumble firm tofu or tempeh and increase beans for protein.
Serving Suggestions
- I love rice or tortillas to scoop up the sauce in Santa Fe Chicken Skillet.
- A bright mix of cilantro, lime, and avocado adds freshness.
Ideal sides and toppings
- I love rice or tortillas to scoop up the sauce in Santa Fe Chicken Skillet.
- A bright mix of cilantro, lime, and avocado adds freshness.
Presentation tips
- I slice the chicken and fan it over the sauce for a look.
- I serve it in a warm skillet to keep heat.
Elevate Your Santa Fe Chicken Skillet: Variations and Add-Ins
Add-ins for extra depth
I love adding a few flavorful add-ins to deepen the Santa Fe Chicken Skillet without slowing me down. These tiny tweaks wake up the pan and your palate. They help the dish feel exciting, even on rushed weeknights.
Try a handful of fresh or pantry-friendly tweaks to customize the flavor. Think a little tang, a touch of heat, and a creamy contrast that makes every bite sing.
- Charred peppers and onions stirred in at the end for a smoky sweetness.
- Cotija or queso fresco crumbles for a salty, creamy crumble on top.
- A dollop of avocado crema or a spoonful of sour cream keeps the cheese from stealing all the richness.
- Thin jalapeño slices or pickled jalapeños for a brighter kick.
- A light squeeze of fresh lime and a handful of chopped cilantro to finish.
These add-ins work with the Santa Fe Chicken Skillet vibe and stay friendly to busy schedules.
Meal-prep-friendly versions
Meal-prep makes this skillet even more approachable. I keep components ready so dinner time feels effortless. When the clock is ticking, I’m grateful for a plan that still tastes like I cooked from scratch.
Build a workflow that travels well from fridge to table. The goal is to have everything you need in reach, so you can plate in moments rather than minutes.
- Pre-measure and mix spices in a small jar the night before; you’ll be ready to season in a flash.
- Chop cilantro and lime ahead and store in a sealed container; add just before serving.
- Cook rice or prepare greens in advance; reheat with a splash of broth to loosen any clumps.
- Prep a batch of Ro-Tel mixture and leftovers that layer back in quickly for lunch bowls.
With these prep habits, your Santa Fe Chicken Skillet becomes a repeatable, no-stress weeknight winner.
Seasonal twists
Seasonal twists keep the dish fresh and aligned with what’s in farmers’ markets. I love leaning into produce that’s at its peak, then adapting the skillet without sacrificing speed.
Here are easy, seasonally inspired tweaks you can try while keeping the core 30-minute magic intact.
- Summer: swap in fresh corn and diced tomatoes; add a splash of pico de gallo and cilantro for a bright, garden-fresh finish.
- Fall: fold in roasted butternut squash or sweet potato chunks halfway through; add a pinch of chipotle powder for warmth.
- Spring: toss in asparagus spears or zucchini ribbons in the last few minutes for crisp-tresh crunch.
- Winter: amp up the cozy factor with a smoky touch of chipotle in adobo and a handful of spinach stirred in at the end.
Seasonal twists keep the Santa Fe Chicken Skillet exciting, while still delivering the same comforting, one-pan practicality you rely on.

FAQs
Can I use chicken thighs instead of breasts?
Yes. I sometimes use boneless thighs for juicier Santa Fe Chicken Skillet.
They need longer searing—about 6–8 minutes per side.
Check for an internal temp of 165°F before serving.
Let them rest a minute to finish cooking for best results.
Is this gluten-free, and can I make it dairy-free?
Yes, the recipe as written is gluten-free.
To make it dairy-free, swap cheese for a dairy-free option or omit it.
Ro-Tel and the other ingredients keep the dish flavorful with or without dairy.
How do I reheat this without drying it out?
Reheat gently in a skillet over low heat with a splash of broth.
Cover to trap moisture, then stir to re-warm evenly.
Leftovers taste best when warmed slowly, keeping the chicken juicy.
Can I freeze leftovers?
Yes. Freeze leftovers in airtight containers for 2–3 months.
Thaw overnight in the fridge before reheating.
Reheat as above; texture may shift slightly but flavors stay bright.
Final Thoughts
The comfort and confidence of a quick, flavorful weeknight dinner
Cooking this Santa Fe Chicken Skillet reminds me why weeknights can feel bright. I love the simple pan, smart spices, and a cheesy finish that calm the chaos. It’s a dish I reach for when time is short but I want flavor that feels like home.
A dish that travels well to family meals and potlucks
When I plate the Santa Fe Chicken Skillet, comfort and confidence rise. The flavors stay reliable, the steps stay simple, and the moment feels warm.
Leftovers travel easily to family meals and potlucks. A quick lime squeeze and cilantro finish keeps it vibrant, and a small dollop of avocado crema adds brightness.
Print
Santa Fe Chicken Skillet 5-Ingredient Bold Delicious Quick.
- Total Time: 30 minutes
- Yield: 4 servings 1x
- Diet: Gluten Free
Description
Santa Fe Chicken Skillet – a bold, quick Tex-Mex dinner featuring pan-seared chicken smothered with Ro-Tel, corn, black beans, and melty cheese.
Ingredients
- 4 boneless, skinless chicken breasts
- 2 tbsp olive oil
- 1 tsp chili powder
- 1 tsp cumin
- ½ tsp paprika
- ½ tsp garlic powder
- Salt and pepper, to taste
- 1 (10 oz) can Ro-Tel diced tomatoes with green chilies
- 1 cup corn kernels (fresh, frozen, or canned)
- 1 cup canned black beans, drained and rinsed
- 1 cup shredded cheddar or Monterey Jack cheese
- 2 tbsp chopped cilantro
- Juice of ½ lime
Instructions
- Season chicken with chili powder, cumin, paprika, garlic powder, salt, and pepper.
- Heat olive oil in a large skillet over medium-high heat. Add chicken and sear for 5–6 minutes per side until golden and cooked through. Remove and set aside.
- In the same skillet, add Ro-Tel tomatoes, corn, and black beans. Stir and simmer for 3–4 minutes to heat through and combine flavors.
- Return chicken to the skillet, spoon the mixture over the top, and sprinkle with shredded cheese.
- Cover and cook on low for 2–3 minutes, until the cheese is melted and bubbly.
- Finish with a squeeze of lime juice and a sprinkle of fresh cilantro. Serve warm with rice, tortillas, or over a salad!
Notes
- You can adjust the spice level by adding more chili powder or a pinch of cayenne.
- Leftovers can be stored covered in the refrigerator for 3–4 days.
- Best with rice, warm tortillas, or over greens for a quick bowl.
- To make it lighter, use reduced-fat cheese or skip cheese altogether.
- Prep Time: 10 minutes
- Cook Time: 20 minutes
- Category: Main Dish
- Method: Skillet, One-Pan
- Cuisine: Tex-Mex
Nutrition
- Serving Size: 1/4 of recipe (about 1 chicken breast with toppings)
- Calories: about 438
- Sugar: about 6 g
- Sodium: about 600-650 mg
- Fat: about 22 g
- Saturated Fat: about 9-11 g
- Unsaturated Fat: about 12-14 g
- Trans Fat: 0 g
- Carbohydrates: about 21-23 g
- Fiber: about 6-7 g
- Protein: about 30 g
- Cholesterol: about 150 mg
Keywords: Santa Fe Chicken Skillet, Tex-Mex skillet, quick dinner, one-pan meal, Ro-Tel, black beans, corn, cheesy chicken